He rose to prominence during the reign of Henry VII, negotiating marriages and treaties. The young King Henry VIII also relied on the Bishop to take care of many details at the beginning of his reign. When Fox finally left Court, encouraged by Wolsey in 1523, he finally turned his attention to his duties as bishop in Winchester.
His greatest legacy was the 1517 foundation Corpus Christi College, with one of the most beautiful main quads at the University of Oxford. Catherine of Aragon visited there and the great Erasmus admired the college library.